Papilloma- Behavior tumor formation of skin and mucous membranes of viral causes.It has a nipple on the narrow base (leg) with soft or dense consistency, ranging from light brown to dark brown.The positioning of papillomas on the skin can cause impaired breathing in the throat, sound, formation of the mucosa of internal organs - ulcers and bleeding.Recurrence of the disease is possible, and the most powerful complication is malignant degeneration.Nipple removal can be performed by electrocoagulation, crying castings, surgical resection, radio wave method or laser exposure.
General information
Papilloma- This is a disease that affects epithelial cells and skin.The cause of papilloma is human papillomavirus, which belongs to the papaya virus family of the papillomavirus group.In HPV, viruses with high and low risk of carcinogenicity are distinguished.Oncogenic papillomas are explained by the virus's ability to integrate their DNA into the human cell genome.
Mechanisms of human papillomavirus infection
Once in the human body, HPV affects the basal cells of the epithelium in the initial stage.Microomas, wrinkles, cracks and other skin injuries help the papillomavirus enter the body.For a long time, the virus can reproduce primarily rather than manifest clinically (chronic carriage).If the virus spreads in the surface layer of the skin, then over time, cell proliferation is observed even in the chronic transport of the papillomavirus.
Since human papillomaviruses are nested in the external environment, infection is direct contact.Strengthening sexual relationships lead to infection; smoking, pregnancy, endometriosis, vitamin deficiency, and immunodeficiency are the triggers, so infection occurs when interacting with the virus.The risk of infection increases with frequent contact with naked skin, such as massage.
Clinical manifestations of papilloma
A papilloma is a tumor of the skin or mucous membrane that looks like a papillary growth that extends over the surrounding tissue.Papillomas are located on the skin, mucosa, inguinal area and genitals, and in some cases papillomas are found in the mucosa of the renal pelvis and ureter.
Because papillomas are composed of connective tissue covering the skin and contain blood vessels, bleeding may occur during trauma.The tumor grows upward in all directions in the form of scattered nipple and looks like cauliflower.
The skin may not change, but in most cases the papilloma color ranges from white to dirty brown.Favorite localization - brush and hands skin.Papillomatosis is common in patients with immunodeficiency.1-6 months after infection, major changes in the skin begin to appear.The virus concentration has reached its maximum for the sixth month since the infection period, which is the most infected period.
The clinical manifestations of papillomas can vary depending on the type of virus.Therefore, the vulgar papilloma has a rough keratinous surface in a solid concave and convex form of 1 mm in diameter.Vulgar papillomas are prone to merge and therefore often affect important areas of the skin.Simple (vulgar) papillomas are locally everywhere, but are more commonly affected by the skin of the fingers and the back of the palm.In children, especially young people, they are affected by papillomas, which is due to physiological characteristics because children do not wear clothes.Usually, vulgar papillomas are located in the group, but an element may exist for a long time over the years.Immunodeficiency conditions and general diseases contribute to the spread of the process, and in isolation, vulgar papillomas are malignant.
The pathogenic drug for papilloma is PAPC 1.2.4.A few months after the sole infection, a small brightness lump appeared, which had all the signs of a common papilloma and was surrounded by prominent edges.In some cases, small-scale subsidiaries appear around a papilloma, with an external similarity to a bubble.Mosaic papillomatosis was then diagnosed.
Papillomas on the soles are often painful, especially when walking.In about 30% of the cases, they are self-dissolved and more self-progression is observed in young children.They are often confused with corn that appears between fingers that have been compressed for a long time.However, unlike papillomas, corn surfaces are smooth and maintain skin pattern.
The pathogenic drug for flat papilloma is HPV 3.10.These unchanged skin-toned papillomas, seen in smooth flat cones, may sometimes have a pale yellow or slightly pink shade, with more often rounded outlines.Several human papillomas were also found.Tumors can cause pain, itching, and hypoxia in the affected area.
Membrane papillomas are diagnosed as half of the people, half of whom are over 50 years old in the skin, and they are also known as Acorodoro.They are located around the eyes, on the skin on the groin, armpits and on the neck.First, a small pale yellow shadow appeared, which further increased and gradually transformed into dense elastic formations up to 5-6mm.If Akro locates the possible places in the place of trauma, they will inflame and harm.The film nipple do not easily disappear spontaneously.Rectal polyps are often observed in patients diagnosed with threaded papilloma.
HPV 13,32 causes local epithelial hyperplasia, characterized by the appearance on the oral mucosa and the red boundary of the lips of the small papillary tumor, slightly elevated above the skin for easy fusion.
One of the rare papillomas found is the papilloma of Lewandovsky-Lutz (Warty epidermis).Mainly children and adolescents get sick.Sometimes, swelling of wart epidermis is a family role.It looks clinically like multiple reddish-brown spotted papillomas on the hands and feet.If papillomas are located in the skin area (most susceptible to UV radiation), in 30% of the cases they are malignant and regenerate into malignant tumors and germinate into adjacent tissues.
HPV is a pointed pathogen that may be a low, medium and high risk of tumor degeneration, so PCR is always required when sharp confectioner sugar is diagnosed.The incubation period is from weeks to months.These papillomas have not yet attracted attention because of the small variation in some cases.The main transmission path is sex.Risk groups include people with immunodeficiency who often change their sexual partners.On the outside, they look like pink or light gray pigmented tips growing.
In most cases, you notice pain, burning, itching, irritation when touching and rubbing with your underwear, frequent injuries and bleeding.They are located on the eve of the vagina, on the labia minora, less frequently, and spicy conworms are found in the vagina and cervix.In men, the holes in the urethra are affected.The injury zone depends on sexual behavior, and sharp condylomas are found in the perineum and hairy areas in people practicing anal contact.In some cases, acoustic dy tumors are diagnosed on the red border of the oral mucosa and lips, again associated with the characteristics of sexual activity.
Juvenile papillomas in the larynx are rarely documented, they are caused by HPV 6.11; in most cases, children under the age of five are sick.The infection occurs during childbirth, when the working woman had papillomas in the vagina while following the birth tube and breathed prematurely.The disease is characterized by papillary growth on the vocal cords, which leads to difficulties in air circulation and speech disorders.
Diagnosis of papilloma
The diagnosis of papilloma is performed by a dermatologist or venologist.Due to the large number of virus types, it has its own characteristics.Only in the classical cases of acne warts, accurate diagnosis can be made based on visual examinations, but this does not provide accurate information about the type of virus and its carcinogenicity.Therefore, if the papillary nature of the tumor is suspected, they resort to PCR diagnosis of viral DNA.
PCR diagnosis not only allows confirmation of the presence and determination of the type of human papillomavirus in the body, but also allows for diagnosis of how many viruses are in the body at the time of analysis.This has diagnostic value because knowing the percentage of the virus content and its type, you can determine the approximate time of infection and identify the person you contact for checking and prescribing preventive treatment.PCR diagnosis also provides information on whether papilloma has a chronic course or results of simultaneous reduction in immunity.Thanks to such data, proper treatment can be prescribed.
If the only treatment is to remove the papilloma, then in parallel with the surgery, biopsy is performed for cytologic studies.Histological examination of papilloma tissue gives more accurate results because the examination is carried out according to the cells, so the correct position of its layer and its structural characteristics.This gives reliable results on the extent of body changes and the possibility of malignant tumors, as long-term and non-tea milky papillomas cause cancer more frequently than detected HPV with high Oncoris.
Typically, PCR diagnosis is screened in nature, and if the analysis confirms the presence of the virus, other studies are performed.
Papillomat therapy
In each case, the treatment regimen for papilloma was selected separately.If HPV is detected during the diagnosis but there is no clinical manifestation, prophylactic therapy is prescribed with a cell inhibitor.It works so well that you can "spread" the virus for years.It is recommended that patients who are HPV carriers undergo PCR regularly and use the barrier method of the contraceptive layer to avoid infection with their partner that harms the human papillary peel.
Inozin pranobex is a drug that treats papilloma from the antiviral group and inhibits the reproduction of the virus.It is one of the most popular because of its immunomodulatory properties.The indication for use is to diagnose papillomas with other viral infections, such as cytomegalovirus infection, measles, and mumps.The presence of herpes virus, chronic viral hepatitis and immunodeficiency also requires the inclusion of isopropylamine in the treatment regimen.Since papilloma therapy is long, papillary pranobex must be performed under the supervision of a doctor, as it is necessary to control laboratory indicators.All HPV patients showed immunomodulatory agents and vitamin treatments use.
If there is manifestation of HPV on the skin and mucosa, litigation depends on papilloma, electrocoagulation or removal of nipple lasers based on location and symptoms.Another modern surgical treatment can be used - the removal of papillomas with radio waves.If the papilloma shows signs of malignant tumors, the scalpel that captures the affected area of healthy tissue is removed.
It should be kept in mind that removing papillomas does not lead to full recovery, as there are no medications detailed on HPV today.Therefore, patients with previously diagnosed papilloma need to undergo regular examinations and undergo antiviral therapy sessions.
Since HPV is primarily sexually transmitted, the only way to prevent papilloma is to prevent contraception.When planning pregnancy, it is necessary to diagnose and, if necessary, treatment for the virus is required to reduce the likelihood of infecting children during childbirth and the first few years of life.